Nettle leaves or root: what does the evidence say?

EMA distinguishes nettle herb from root. Aerial parts cover specific traditional uses for minor urinary complaints and joint pain; root concerns urinary symptoms linked to benign prostatic hyperplasia after serious causes are excluded by a doctor.

A recent review pooled six randomized trials involving 1,210 participants. A favorable signal had very low certainty because of bias, heterogeneity and imprecision. One 620-person trial was favorable; a 49-person nettle-Pygeum trial did not differ significantly from placebo.

Check whether the label says aerial parts or root, then identify the preparation. Root-extract evidence cannot automatically be transferred to leaf tea. Avoid universal detox claims.

References are listed in the validated evidence dossier.